Endocrine Abstracts

Issue: Macroprolactin (MPRL) is a high molecular mass complex of prolactin with minimal bioactivity in vivo that may be the cause of elevated serum prolactin (PRL) as determined by immunoassay. Unrecognised macroprolactinemia can lead to misdiagnosis and mistreatment. The frequency of MPRL is highly dependent on the affinity of the antibody used in the assay.The aim of this study: Was to compare the frequency and quantity of MPRL measured by a first and ...